GSK and Genmab seek alternative approval for leukaemia drug Arzerra

New Drug Approvals


GlaxoSmithKline and Genmab A/S have announced the submission of leukaemia drug Arzerra to the European Medicines Agency (EMA) for a variation in marketing authorisation.

The companies are seeking authorisation for the drug to be used in combination with an alkylator-based therapy for treatment of Chronic Lymphocytic Leukemia (CLL) patients who have not received prior treatment and are inappropriate for fludarabine-based therapy.


Ofatumumab(trade name Arzerra, also known as HuMax-CD20) is a humanmonoclonal antibody (for the CD20 protein) which appears to inhibit early-stage B lymphocyte activation. It is FDA approved for treating chronic lymphocytic leukemia that is refractory to fludarabine and alemtuzumab (Campath) and has also shown potential in treating Follicular non-Hodgkin’s lymphoma, Diffuse large B cell lymphoma, rheumatoid arthritis and relapsing remitting multiple sclerosis. Ofatumumab has also received conditional approval in Europe for the treatment of refractory chronic lymphocytic leukemia…

View original post 426 more words

Wartsila awarded turnkey order for PLN subsidiary’s


Keep posting

Energy Journal

Power-Plant-dan-BaliFinland’s Wartsila said it has secured an order from a subsidiary of Indonesia’s state-owned PLN to help build a 200MW power plant that will be the country’s largest when it is fully operational by May 2015.

Wartsila will lead PT Pembangunan Perumahan (Persero) Tbk (PT PP), one of Indonesia’s largest construction contractors, in a consortium to build PT Indonesia Power’s Pesanggaran Bali power plant to meet Bali Island’s rising electricity demand.

The plant will supply electricity to Bali’s sub system grid when it begins operating from December 2014. Operating on Wartsila’s modern combustion engine technology, the plant will be powered by 12 of its 50DF dual-fuel engines feeding mostly on natural gas with the flexibility to swtich to conventional heavy fuel oil when needed.

The Helsinki-based firm said the order strengthens its position as one of the world’s leading suppliers of large gas and multi-fuel power plants of up to…

View original post 183 more words

Green development


Art at the push of a button

The “garbage mountain” in Fröttmaning in north Munich used to be a stinking, festering, poisonous mountain of, well …, garbage in the 60’s.

Opened in the early 50’s as a garbage disposal landfill, it soon grew to mountainous proportions becoming a major source of atmospheric and underground water pollution for north Munich.

Finally, in the 70’s and 80’s it was closed down as a landfill, sealed from all sides with concrete and converted into an iconic hill.

The wind turbine on top of it was built in 1999 and has since become a landmark of north Munich and of the northern city entrance (the A9 Motorway leading into Munich passes right next to it). This hill with the turbine is now a symbol of environmental consciousness and green development for Munich and one of the prime locations for enjoying a walk and a wonderful view of the city with the…

View original post 230 more words

How the use of wind power helped in making the environment a better place

Technology improves the way that we live

Wind power is the conversion of wind energy into a useful form of energy, such as for example using wind turbines in order to make electrical power, windmills for the use of mechanical power, wind pumps for pumping water and for drainage, or sails to propel ships.

Wind power, as an alternative to fossil fuels can be plentiful, renewable, widely distributed, clean, and it also produces no greenhouse gas emissions during operation and uses little land. In other words, wind power consumes no fuel and emits no air pollution.

Compared to the environmental impact of traditional energy sources, the environmental impact of wind power is relatively minor in terms of pollution. The energy consumed to manufacture and transport the materials used to build a wind power plant is equal to the new energy produced by the plant within a few months. While a wind farm may cover a large area of land, many land uses such as agriculture are compatible, with only…

View original post 83 more words


Tribhuvan International Airport



Tribhuvan International Airport

Tribhuvan International Airport is facing heavy congestion with busy runways and limited space for aircraft storage and expected to handle 5.85 million passengers by 2015. The expansion will generate 500 direct jobs during construction and 2,000 new jobs post expansion. Read more @